![]() ![]() Ways to increase NAD+ include NAD+ patches, IV therapy, and supplements that increase NAD+, such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN). 6 NAD+ therapy can stimulate the healing processes in your body, even though many people need to start slowly. Low NAD+ is a marker of mitochondrial dysfunction, cellular aging, and neurodegenerative diseases. Nicotinamide adenine dinucleotide (NAD+), which is an important metabolic cofactor.Treatments I often use for cellular aging and mitochondrial dysfunction include: Oxidative stress can cause biological aging, which is a common contributor to cognitive decline, along with chronic inflammation that affects the whole body. These factors may include anemia, sleep apnea, poor posture, poor circulation, and too low or too high blood pressure. While some nootropics can increase blood flow to the brain, it is important to address factors that can affect brain blood flow and oxygen delivery. Lack of oxygen can contribute to mitochondrial dysfunction and increase oxidative stress, leading to brain fog. Oxygen is important for mitochondrial function. This will expose you to excessive oxidative stress.įortunately, you can increase your antioxidant capacity and resilience to these factors by eating more antioxidant-rich foods and using the right supplements and biohacks. There are a few potential contributors to high oxidative stress in the brain. You may even start to experience weight gain and other conditions of aging. As a result, you’ll feel tired and brain fog. ![]() These can damage your cells and the mitochondria inside them, causing cellular aging and reducing your ability to produce energy (ATP). Oxidative stress can inhibit mitochondrial function, creating more oxidative stress and inflammation. Your brain cells are heavily dependent on the mitochondria (tiny energy factories within the cells) for energy. 4Ģ) Oxidative stress, mitochondrial dysfunction, and aging Low doses (1 – 5 mg/day) can reduce neuroinflammation caused by glial cells. Low-dose naltrexone – naltrexone is an opioid antagonist.2 Spermidine supplementation improves cognitive function and protects against age-related memory impairment. Spermidine – enhances the cellular renewal process where your cells and neurons literally eat their old components to reuse the building blocks.Some of the treatments that I use to help my patients with neuroinflammation include: If you’re struggling with brain fog, it is important to investigate possible sources of neuroinflammation and address them accordingly. At the same time, it increases toxic neurotransmitter metabolites that are linked to depression. Neuroinflammation increases glutamate levels in your brain and reduces brain-derived neurotrophic factor. Too much glutamate jams nerve cell communications, killing them and causing brain fog. Glutamate is a very important and most abundant excitatory neurotransmitter in your brain, but you want to have just the right amount. Inflammation from lifestyle sources can activate these immune cells and prime them to react with more inflammation. They protect your brain from germs and also help clean up the damage, misfolded proteins, and cellular wastes. Concussions or mild traumatic brain injuries, even ones from decades agoĪside from neurons, there are also immune cells, such as astrocytes and glial cells, in your brain.Deficiencies of nutrients required for balanced immune function, such as vitamin D.An imbalance of the gut bacteria (dysbiosis).Unhealthy diets and food-related inflammation.The inflammation could come from any of the following: 1) Neuroinflammationīrain fog, fatigue, lack of motivation, and mental health issues can be symptoms of neuroinflammation. The following are the potential root causes that we test for and address among our executive clients who struggle with brain fog, focus, and daytime fatigue. What causes brain fog?Īn intense lifestyle of always being on the run, working around the clock, eating out, and constantly traveling can wear down on your body and, thus, your brain. So, in this article, we’ll first cover the root causes of brain fog and then look at the common nootropics for brain fog. Nootropics can help but they will not replace the basics that your body needs for optimal brain function. With our 360 o approach, we’ve had great success combining nootropics with addressing individual root causes of brain fog for hundreds of executives like you. Yet, sometimes brain fog, forgetfulness, and fatigue start to set in, so you’re looking for nootropics (brain-enhancing supplements and drugs) and other means to help you stay at the top of your game. You’re finally getting paid for your intellectual capital and brain performance under pressure. You’ve worked hard to be where you’re at in your career. ![]()
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